Autologous vs Allogeneic
Autologous cells come from the patient. Allogeneic cells come from a healthy donor and require no HLA matching when MSCs are used.
Cell Sources
What is Autologous vs Allogeneic?
An autologous cell therapy uses cells harvested from the patient themselves (commonly bone marrow or adipose). An allogeneic therapy uses cells from a healthy young donor — at TurkeyStemcell, full-term umbilical cord Wharton's Jelly donors. Because MSCs express low levels of HLA Class II and are considered immune-privileged, allogeneic MSCs do not require HLA matching and consistently outperform aged autologous cells in proliferation, paracrine activity and reproducibility of dose.
Related terms in Cell Sources
Mesenchymal Stem Cells (MSCs)
Multipotent adult stem cells that regulate inflammation and tissue repair. Sourced from umbilical cord, bone marrow, or adipose tissue.
Wharton's Jelly
The gelatinous tissue inside the umbilical cord — the richest source of young, highly proliferative mesenchymal stem cells.
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